Risk (OR-ad) of
lung cancer depending on adsorbed lung
dose due to 239Pu incorporation
and smoking index
Adsorbed Lung Dose (Gy)
The dose-response
relationshipfor plutonium
incorporation corresponded to non-linear threshold relationship. Such a a
relationship proved tobe most cleary manifested for adenocarcinoma. The
threshold was 3.7 kBq for Pu body burden or 0.8 Gy for absorbed lung dose. Dose-effect
for smoking had a linear character and was the highest for squamous-cell
carcinoma.
We have not obtained
convincing data characterizinga
dose-effect for chronic external gamma-irradiation.